Gene information
Official symbol SAA1
Official full name serum amyloid A1
Gene type protein-coding gene
Chromosome11p15.1
Alias symbolPIG4; TP53I4
Previous symbolSAA
Gene familyReceptor ligands
Resources
Entrez Gene 6288
HGNC HGNC:10513
Ensembl ENSG00000173432
Vega OTTHUMG00000166147
UCSC uc057zpu.1
GO terms: 52 records
GO Description Category LogP Number of genes Detail
GO:0001664 G protein-coupled receptor binding GO Molecular Functions -22.7408810 35 More
GO:0001775 cell activation GO Biological Processes -43.3738118 71 More
GO:0001819 positive regulation of cytokine production GO Biological Processes -44.1872667 64 More
GO:0002526 acute inflammatory response GO Biological Processes -34.5980034 29 More
GO:0005539 glycosaminoglycan binding GO Molecular Functions -36.7680176 44 More
GO:0006935 chemotaxis GO Biological Processes -33.1726887 55 More
GO:0006953 acute-phase response GO Biological Processes -24.9631834 19 More
GO:0006954 inflammatory response GO Biological Processes -86.5569367 100 More
GO:0007204 positive regulation of cytosolic calcium ion concentration GO Biological Processes -15.6883547 39 More
GO:0007596 blood coagulation GO Biological Processes -44.7281461 45 More
GO:0007599 hemostasis GO Biological Processes -44.1075001 45 More
GO:0008201 heparin binding GO Molecular Functions -33.5542939 37 More
GO:0009611 response to wounding GO Biological Processes -63.1714102 77 More
GO:0030139 endocytic vesicle GO Cellular Components -10.5530816 23 More
GO:0030155 regulation of cell adhesion GO Biological Processes -41.8400792 131 More
GO:0030168 platelet activation GO Biological Processes -17.9354931 20 More
GO:0030593 neutrophil chemotaxis GO Biological Processes -16.9449855 18 More
GO:0030595 leukocyte chemotaxis GO Biological Processes -30.6401488 33 More
GO:0031347 regulation of defense response GO Biological Processes -64.5971043 148 More
GO:0031348 negative regulation of defense response GO Biological Processes -30.3795513 65 More
GO:0032102 negative regulation of response to external stimulus GO Biological Processes -54.2675416 110 More
GO:0032652 regulation of interleukin-1 production GO Biological Processes -24.2088254 41 More
GO:0032732 positive regulation of interleukin-1 production GO Biological Processes -14.7376831 16 More
GO:0032994 protein-lipid complex GO Cellular Components -17.0133835 14 More
GO:0034358 plasma lipoprotein particle GO Cellular Components -17.5986271 14 More
GO:0034364 high-density lipoprotein particle GO Cellular Components -15.5094832 12 More
GO:0042060 wound healing GO Biological Processes -56.2139708 65 More
GO:0042330 taxis GO Biological Processes -33.0828571 55 More
GO:0045785 positive regulation of cell adhesion GO Biological Processes -29.6368249 50 More
GO:0048246 macrophage chemotaxis GO Biological Processes -8.11586193 6 More
GO:0048247 lymphocyte chemotaxis GO Biological Processes -6.64704408 8 More
GO:0050708 regulation of protein secretion GO Biological Processes -30.3716714 63 More
GO:0050727 regulation of inflammatory response GO Biological Processes -68.5964592 121 More
GO:0050728 negative regulation of inflammatory response GO Biological Processes -31.0556128 55 More
GO:0050817 coagulation GO Biological Processes -44.4773041 45 More
GO:0050878 regulation of body fluid levels GO Biological Processes -57.9546976 69 More
GO:0050900 leukocyte migration GO Biological Processes -39.9164759 46 More
GO:0051046 regulation of secretion GO Biological Processes -54.0079540 130 More
GO:0051223 regulation of protein transport GO Biological Processes -25.2801266 81 More
GO:0060326 cell chemotaxis GO Biological Processes -35.3882493 41 More
GO:0070201 regulation of establishment of protein localization GO Biological Processes -24.4831554 82 More
GO:0071621 granulocyte chemotaxis GO Biological Processes -16.4324548 18 More
GO:0071674 mononuclear cell migration GO Biological Processes -16.6998600 20 More
GO:0071682 endocytic vesicle lumen GO Cellular Components -9.48174775 8 More
GO:0072676 lymphocyte migration GO Biological Processes -7.69367801 10 More
GO:0097529 myeloid leukocyte migration GO Biological Processes -25.8454617 28 More
GO:0097530 granulocyte migration GO Biological Processes -19.1764933 21 More
GO:1901681 sulfur compound binding GO Molecular Functions -28.2504512 39 More
GO:1903530 regulation of secretion by cell GO Biological Processes -45.6472055 114 More
GO:1905517 macrophage migration GO Biological Processes -7.27705643 6 More
GO:1990266 neutrophil migration GO Biological Processes -18.6358512 20 More
GO:1990777 lipoprotein particle GO Cellular Components -17.5986271 14 More
Drug-Gene interaction
view
Related drugs: 2 records
Drug name Interaction type Source PMID View
anakinra NCI 1717568 view
naproxen NCI 1729367 view
Related studies: 10 records
Molecular factor Omics type Application Objective MI type Reference
serum amyloid A-1 protein proteomics acute myocardial infarction[diagnosis] acute myocardial infarction Maury CP et al. J Clin Pathol. 1988
serum amyloid A-1 protein proteomics C-reactive protein[other] acute myocardial infarction Marhaug G et al. Acta Med Scand. 1986
serum amyloid A-1 protein proteomics predictor death[prognosis (bad)] acute myocardial infarction Casl MT et al. Ann Clin Biochem. 1995
serum amyloid A-1 protein proteomics plaque rupture[other] acute myocardial infarction Maier W et al. Circulation. 2005
serum amyloid A-1 protein proteomics multiple complex coronary lesions[prognosis (bad)] acute non-ST elevation myocardial infarction Zairis MN et al. Atherosclerosis. 2005
serum amyloid A-1 protein proteomics death[prognosis (bad)] acute ST elevation myocardial infarction Katayama T et al. Circ J. 2005
NM_000331.6:c.288T>C genomics myocardial infarction[diagnosis] myocardial infarction Wang BY et al. Genet Mol Res. 2014
serum amyloid A-1 protein proteomics recurrent cardiac events[prognosis (bad)] acute myocardial infarction Ridker PM et al. Circulation. 1998
serum amyloid A-1 protein proteomics subacute stent thrombosis[prognosis (bad)] acute ST elevation myocardial infarction Katayama T et al. Circ J. 2006
serum amyloid A-1 protein proteomics cardiac rupture[prognosis (bad)] acute ST elevation myocardial infarction Katayama T et al. Circ J. 2006
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